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dihydropyrimidine dehydrogenase : ウィキペディア英語版 | dihydropyrimidine dehydrogenase
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation. It is the initial and rate-limiting step in pyrimidine catabolism. It catalyzes the reduction of uracil and thymine. It is also involved in the degradation of the chemotherapeutic drugs 5-fluorouracil and Tegafur-uracil. ==See also==
* Dihydropyrimidine dehydrogenase deficiency
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